artículo de publicación periódica.page.titleprefix
Control-oriented model with intra-patient variations for an artificial pancreas

dc.contributor.authorMoscoso-Vásquez, Marcela
dc.contributor.authorColmegna, Patricio
dc.contributor.authorRosales, Nicolás
dc.contributor.authorGarelli, Fabricio
dc.contributor.authorSánchez-Peña, Ricardo
dc.date.accessioned2020-03-18T12:47:10Z
dc.date.available2020-03-18T12:47:10Z
dc.date.issued2020
dc.description.abstract"In this work, a low-order model designed for glucose regulation in Type 1 Diabetes Mellitus (T1DM) is obtained from the UVA/Padova metabolic simulator. It captures not only the nonlinear behavior of the glucose-insulin system, but also intrapatient variations related to daily insulin sensitivity (SI) changes. To overcome the large inter-subject variability, the model can also be personalized based on a priori patient information. The structure is amenable for linear parameter varying (LPV) controller design, and represents the dynamics from the subcutaneous insulin input to the subcutaneous glucose output. The eficacy of this model is evaluated in comparison with a previous control-oriented model which in turn is an improvement of previous models. Both models are compared in terms of their open- and closed-loop differences with respect to the UVA/Padova model. The proposed model outperforms previous T1DM control oriented models, which could potentially lead to more robust and reliable controllers for glycemia regulation."en
dc.identifier.urihttp://ri.itba.edu.ar/handle/123456789/1906
dc.language.isoenen
dc.relationinfo:eu-repo/grantAgreement/Fundación Nuria/AR. Ciudad Autónoma de Buenos Aires
dc.relationinfo:eu-repo/grantAgreement/CONICET/PIP/112-201501-00837/AR. Ciudad Autónoma de Buenos Aires
dc.relationinfo:eu-repo/grantAgreement/JDRF/APF/2-APF-2019-373-A-N/US. Nueva York. NY
dc.relationinfo:eu-repo/grantAgreement/Fundación Cellex/SP. Barcelona
dc.relationinfo:eu-repo/grantAgreement/ANPCyT/PICT/2017-3211/AR. Ciudad Autónoma de Buenos Aires
dc.relationinfo:eu-repo/semantics/altIdentifier/doi10.1109/JBHI.2020.2969389
dc.subjectORGANOS ARTIFICIALESes
dc.subjectPANCREASes
dc.subjectDIABETESes
dc.subjectINSULINAes
dc.subjectCONTROL ROBUSTOes
dc.subjectGLUCOSAes
dc.titleControl-oriented model with intra-patient variations for an artificial pancreasen
dc.typeArtículos de Publicaciones Periódicases
dc.typeinfo:eu-repo/semantics/acceptedVersion
dspace.entity.typeArtículo de Publicación Periódica
itba.description.filiationFil: Moscoso-Vásquez, Marcela. Instituto Tecnológico de Buenos Aires; Argentina.
itba.description.filiationFil: Moscoso-Vásquez, Marcela. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina.
itba.description.filiationFil: Colmegna, Patricio. University of Virginia; Estados Unidos.
itba.description.filiationFil: Colmegna, Patricio. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina.
itba.description.filiationFil: Colmegna, Patricio. Universidad Nacional de Quilmes; Argentina.
itba.description.filiationFil: Rosales, Nicolás. Universidad Nacional de La Plata; Argentina.
itba.description.filiationFil: Garelli, Fabricio. Universidad Nacional de La Plata; Argentina.
itba.description.filiationFil: Garelli, Fabricio. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina.
itba.description.filiationFil: Sánchez-Peña, Ricardo. Instituto Tecnológico de Buenos Aires; Argentina.
itba.description.filiationFil: Sánchez-Peña, Ricardo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina.

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