ponencia en congreso.page.titleprefix
Time estimation of topotecan penetration in retinoblastoma cells through image sequence analysis

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dc.contributor.authorChan, Debora
dc.contributor.authorWinter, Úrsula
dc.contributor.authorSchaiquevich, Paula
dc.contributor.authorRamele, Rodrigo
dc.contributor.authorGambini, Juliana
dc.date.accessioned2020-04-01T14:45:26Z
dc.date.available2020-04-01T14:45:26Z
dc.date.issued2020
dc.description.abstract"Retinoblastoma is the most common intraocular tumor in childhood. Topotecan has been widely used as an antineoplastic agent for retinoblastoma treatment. Topotecan penetration into living tumorspheres is quantified using confocal microscopy. This fluorescent drug dyes the living tissue and it can be recorded in a sequence of images over a period of time. The effective penetration of the drug depends on culture characteristics and requires a very specific timing. This penetration time is calculated empirically by an expert. The purpose of this work is to offer a statistical model to automatically estimate the penetration time of topotecan in the cell, based on the information obtained from a sequence of tumorsphere images."en
dc.identifier.isbn978-3030-30-647-2
dc.identifier.issn1680-0737
dc.identifier.urihttp://ri.itba.edu.ar/handle/123456789/1923
dc.language.isoenen
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/10.1007/978-3-030-30648-9_35
dc.subjectRETINOBLASTOMAes
dc.subjectPROCESAMIENTO DE IMAGENESes
dc.subjectDIAGNOSTICO POR IMAGENESes
dc.subjectTUMORESes
dc.subjectESTADISTICAes
dc.subjectSEGMENTACION DE IMAGENESes
dc.titleTime estimation of topotecan penetration in retinoblastoma cells through image sequence analysisen
dc.typePonencias en Congresoses
dc.typeinfo:eu-repo/semantics/acceptedVersion
dspace.entity.typePonencia en Congreso
itba.description.filiationFil: Chan, Debora. Universidad Tecnológica Nacional. Facultad Regional Buenos Aires; Argentina.
itba.description.filiationFil: Ramele, Rodrigo. Instituto Tecnológico de Buenos Aires; Argentina.
itba.description.filiationFil: Gambini, Juliana. Universidad Tecnológica Nacional. Facultad Regional Buenos Aires; Argentina.
itba.description.filiationFil: Gambini, Juliana. Instituto Tecnológico de Buenos Aires; Argentina.
itba.description.filiationFil: Gambini, Juliana. Universidad Nacional de Tres de Febrero; Argentina.
itba.description.filiationFil: Gambini, Juliana. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina.
itba.description.filiationFil: Winter, Úrsula. Hospital de Pediatría Garrahan; Argentina.
itba.description.filiationFil: Winter, Úrsula. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina.
itba.description.filiationFil: Schaiquevich, Paula. Hospital de Pediatría Garrahan; Argentina.
itba.description.filiationFil: Schaiquevich, Paula. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina.

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