artículo de publicación periódica.page.titleprefix
Positive and neutral updating reconsolidate aversive episodic memories via different routes

dc.contributor.authorWang, Jingyi
dc.contributor.authorChen, Boxuan
dc.contributor.authorSha, Manqi
dc.contributor.authorGu, Yiran
dc.contributor.authorWu, Haitao
dc.contributor.authorForcato, Cecilia
dc.contributor.authorQin, Shaozheng
dc.date.accessioned2021-02-05T18:14:48Z
dc.date.available2021-02-05T18:14:48Z
dc.date.issued2021-01
dc.description.abstract"Aversive memories are long-lasting and prone to have adverse effects on our emotional wellbeing and mental health. Yet, how to remedy the maladaptive effects of aversive memories remains elusive. Using memory reactivation and emotional updating manipulations, we investigated how positive and neutral emotion updates aversive memories for reconsolidation in humans. We found that positive updating after reactivation was equivalent to neutral updating in altering true memories of the aversive story, but introduced more false memory. Moreover, an additional 12 hours of sleep reconsolidation did not further enlarge true memory differences, but attenuated the effect of reactivation and updating on false memory. Interestingly, the neutral rather than the positive updating reduced the emotional arousal of the aversive memory 24 hours later. Our findings provide novel insights into real-world therapeutic applications regarding how updating with positive and neutral emotion may reshape aversive memories, especially when taking wake- and sleep-filled reconsolidation into account."en
dc.identifier.urihttp://ri.itba.edu.ar/handle/123456789/3361
dc.language.isoenen
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/10.1101/2021.01.04.424701
dc.relationinfo:eu-repo/grantAgreement/NSFC/31522028/CN. Beijing
dc.relationinfo:eu-repo/grantAgreement/NSFC/81571056/CN. Beijing
dc.relationinfo:eu-repo/grantAgreement/BNU/CNLZD1503/CN. Beijing
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectCONSOLIDACION DE LA MEMORIAes
dc.titlePositive and neutral updating reconsolidate aversive episodic memories via different routesen
dc.typeArtículos de Publicaciones Periódicases
dc.typeinfo:eu-repo/semantics/publishedVersion
dspace.entity.typeArtículo de Publicación Periódica
itba.description.filiationFil: Wang, Jingyi. Beijing Normal University; China
itba.description.filiationFil: Chen, Boxuan. Beijing Normal University; China
itba.description.filiationFil: Sha, Manqi. Beijing Normal University; China
itba.description.filiationFil: Gu, Yiran. East China Normal University; China
itba.description.filiationFil: Wu, Hiato. Chinese Academy of Medical Sciences; China
itba.description.filiationFil: Wu, Hiato. Chinese Institute for Brain Research; China
itba.description.filiationFil: Forcato, Cecilia. Instituto Tecnológico de Buenos Aires; Argentina
itba.description.filiationFil: Qin, Shaozheng. Beijing Normal University; China
itba.description.filiationFil: Qin, Shaozheng. Chinese Institute for Brain Research; China

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