(2017) Roitman, Pablo D.; Farfalli, Germán L.; Ayerza, Miguel A.; Múscolo, D. Luis; Milano, Federico E.; Aponte-Tinao, Luis A.
"Central chondrosarcoma of bone is graded on a scale of 1 to 3 according to histological criteria.
Clinically, these tumors can be divided into low-grade (Grade 1) and high-grade (Grade 2, Grade 3, and dedifferentiated) chondrosarcomas. Although en bloc resection has been the most widely used treatment, it has become generally accepted that in selected patients with low-grade chondrosarcomas of long bones, curettage is safe and effective. This approach requires an accurate preoperative estimation of grade to avoid under- or overtreatment, but prior reports have indicated that both imaging and biopsy do not always give an accurate prediction of grade."