Browsing by Author "Gondhalekar, Ravi"
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ponencia en congreso.listelement.badge Control-oriented linear parameter-varying model for glucose control in type 1 diabetes(2016) Colmegna, Patricio; Sánchez-Peña, Ricardo; Gondhalekar, Ravi"The contribution of this paper is a controller design oriented model of insulin-glucose dynamics in Type 1 Diabetes Mellitus (T1DM). The novelty of the proposed model is to more effectively include the time-varying nature, and also the inter-patient variability, associated with the glucose control problem. Importantly, this is achieved in a manner that straightforwardly facilitates well-known and standard controller synthesis procedures. In that way, an average Linear Parameter-Varying (LPV) model that captures the dynamics from the insulin delivery input to the subcutaneous-glucose concentration output is constructed based on the Universities of Virginia (UVA)/Padova metabolic simulator. In addition, a system-oriented reinterpretation of the classical ad-hoc 1800 rule is applied to adapt the model’s gain."artículo de publicación periódica.listelement.badge Linear parameter-varying model to design control laws for an artificial pancreas(2018-02) Colmegna, Patricio; Sánchez-Peña, Ricardo; Gondhalekar, Ravi"The contribution of this work is the generation of a control-oriented model for insulin-glucose dynamic regulation in type1 diabetes mellitus (T1DM). The novelty of this model is that it includes the time-varying nature, and the inter-patient variability of the glucose-control problem. In addition, the model is well suited for well-known and standard controller synthesis procedures. The outcome is an average linear parameter-varying (LPV) model that captures the dynamics from the insulin delivery input to the glucose concentration output constructed based on the UVA/Padova metabolic simulator. Finally, a system-oriented reinterpretation of the classical ad-hoc 1800 rule is applied to adapt the model’s gain."artículo de publicación periódica.listelement.badge Reducing glucose variability due to meals and postprandial exercise in TI DM using switched LPV control: in silico studies(2016) Colmegna, Patricio; Sánchez-Peña, Ricardo; Gondhalekar, Ravi; Dassau, Eyal; Doyle III, Frank J."Time-varying dynamics is one of the main issues for achieving safe blood glucose control in type I diabetes mellitus (TI DM) patients. In addition, the typical disturbances considered for controller design are meals, which increase the glucose level, and physical activity (PA), which increases the subject's sensitivity to insulin. In previous works the authors have applied a linear parameter-varying (LPV) control technique to manage unannounced meals."artículo de publicación periódica.listelement.badge Switched LPV glucose control in type 1 diabetes(2016-06) Colmegna, Patricio; Sánchez-Peña, Ricardo; Gondhalekar, Ravi; Dassau, Eyal; Doyle III, Frank J."The purpose of this work is to regulate the blood glucose level in Type 1 Diabetes Mellitus (T1DM) patients with a practical and flexible procedure that can switch amongst a finite number of distinct controllers, depending on the user´s choice."