Is needle biopsy clinically useful in preoperative grading of central chondrosarcoma of the pelvis and long bones?

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2017
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Roitman, Pablo D.
Farfalli, Germán L.
Ayerza, Miguel A.
Múscolo, D. Luis
Milano, Federico E.
Aponte-Tinao, Luis A.
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"Central chondrosarcoma of bone is graded on a scale of 1 to 3 according to histological criteria. Clinically, these tumors can be divided into low-grade (Grade 1) and high-grade (Grade 2, Grade 3, and dedifferentiated) chondrosarcomas. Although en bloc resection has been the most widely used treatment, it has become generally accepted that in selected patients with low-grade chondrosarcomas of long bones, curettage is safe and effective. This approach requires an accurate preoperative estimation of grade to avoid under- or overtreatment, but prior reports have indicated that both imaging and biopsy do not always give an accurate prediction of grade."
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