Artículo de Publicación Periódica:
Automatic glucose control during meals and exercise in type 1 diabetes: proof-of-concept in silico tests using a switched LPV approach

dc.contributor.authorColmegna, Patricio
dc.contributor.authorBianchi, Fernando D.
dc.contributor.authorSánchez-Peña, Ricardo
dc.dateinfo:eu-repo/date/embargoEnd/2023-03-17
dc.date.accessioned2021-01-22T13:49:34Z
dc.date.available2021-01-22T13:49:34Z
dc.date.issued2021
dc.description.abstract"Keeping the blood glucose levels within the safe range during meals and exercise still represents a major hurdle not only for patients with type 1 diabetes (T1D), but also for Artificial Pancreas (AP) systems. One of the reasons a fully (autonomous) closed-loop solution has not been released onto the market yet is the slow action of current insulin analogs. To partially overcome this limitation, the authors have previously designed a switched control strategy equipped with an insulin-on-board (IOB) safety loop that mitigates meal-related glucose excursions without carbohydrate counting. In this paper, a similar strategy based on a Linear Parameter-Varying (LPV) control law has been adapted to safely handle also exercise challenges with minimum user intervention. In silico results using the UVA/Padova simulator evidence that the proposed closedloop scheme is feasible under moderate-intense exercise bouts by effectively and safely reducing the risk of hypoglycemia."en
dc.identifier.issn2475-1456
dc.identifier.urihttp://ri.itba.edu.ar/handle/123456789/3312
dc.language.isoenen
dc.relationinfo:eu-repo/semantics/reference/10.1109/LCSYS.2020.3041211
dc.relationinfo:eu-repo/grantAgreement/Fundación Cellex/ES. Barcelona
dc.relationinfo:eu-repo/grantAgreement/Fundación Nuria/AR. Ciudad Autónoma de Buenos Aires
dc.relationinfo:eu-repo/grantAgreement/JDRF/APF/2-APF-2019-373-A-N/US. Nueva York, NY
dc.rightsinfo:eu-repo/semantics/embargoedAccess
dc.subjectDIABETESen
dc.subjectPANCREASen
dc.subjectORGANOS ARTIFICIALESen
dc.subjectCONTROL DE VARIACION LINEAL DE PARAMETROSen
dc.subjectINSULINAen
dc.subjectGLUCOSAen
dc.titleAutomatic glucose control during meals and exercise in type 1 diabetes: proof-of-concept in silico tests using a switched LPV approachen
dc.typeArtículos de Publicaciones Periódicasen
dc.typeinfo:eu-repo/semantics/acceptedVersion
dspace.entity.typeArtículo de Publicación Periódica
itba.description.filiationFil: Colmegna, Patricio. University of Virginia; Estados Unidos.
itba.description.filiationFil: Colmegna, Patricio. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina.
itba.description.filiationFil: Bianchi, Fernando D. Instituto Tecnológico de Buenos Aires; Argentina.
itba.description.filiationFil: Bianchi, Fernando D. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina.
itba.description.filiationFil: Sánchez-Peña, Ricardo. Instituto Tecnológico de Buenos Aires; Argentina.
itba.description.filiationFil: Sánchez-Peña, Ricardo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina.

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