Loading...
Non-linear susceptibility to interferences in declarative memory formation
Moyano, Malen D. Carbonari, Giulia Bonilla, Matías Pedreira, María Eugenia Brusco, Luis Ignacio Kaczer, Laura Forcato, Cecilia
Moyano, Malen D.
Carbonari, Giulia
Bonilla, Matías
Pedreira, María Eugenia
Brusco, Luis Ignacio
Kaczer, Laura
Forcato, Cecilia
Type
Artículo
Citations
Altmetric:
Abstract
"After encoding, memories go through a labile state followed by a stabilization process known as consolidation. Once consolidated they can enter a new labile state after the presentation of a reminder of the original memory, followed by a period of re-stabilization (reconsolidation). During these periods of lability the memory traces can be modified. Currently, some studies show a rapid stabilization after 30 min, while others show that stabilization occurs after longer periods (e.g. > 6 h). Here we investigate the effect of an interference treatment on declarative memory consolidation, comparing distinct time intervals after
acquisition. On day 1, participants learned a list of non- syllable pairs (List 1). 5 min, 30 min, 3 h or 8 h later, they received an interference list (List 2) that acted as an amnesic agent. On day 2 (48 h after training) participants had to recall List 1 first, followed by List 2. We found that the List 1 memory was susceptible to interference when List 2 was administered 5 min or 3 h after learning but not when it was administered 30 min or 8 h after. We propose the possibility that this rapid memory protection could be induced by a fast and transient neocortical integration. Our results open a discussion about the contribution of molecular and systemic aspects to memory consolidation."
Description
Date
2022-06-29
Journal Title
Journal ISSN
Volume Title
Publisher
Collections
Files
Loading...
Articulo_Moyano
Adobe PDF, 1.28 MB
Research Projects
Organizational Units
Journal Issue
Keywords
CONSOLIDACION DE LA MEMORIA, MEMORIA, CEREBRO