Neurociencias
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Examinando Neurociencias por Autor "Bonilla, Matías"
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Póster Declarative memory consolidation dynamics: new time windows and its implications for clinical application(2020) Moyano, Malen D.; Bonilla, Matías; Blanco, Marcelo F.; Brusco, Luis Ignacio; Pedreira, María Eugenia; Kaczer, Laura; Forcato, Cecilia"After encoding, memories go through a labile state followed by a stabilization process known as consolidation. Once consolidated they can enter a new labile state after the presentation of a reminder (cue) of the original memory, followed by a period of re-stabilization (reconsolidation). In both processes, once stabilization/re-stabilization is accomplished the memory cannot be modified. Currently there are studies that show a rapid stabilization after 30 min, while others studies show that stabilization occurs after 6h. However, there are no studies evaluating short and long delays simultaneously. Knowing that there are spontaneous waves of destabilization (without the re-exposure to keys linked to learning) on which the consolidation and memory persistence depend, here we investigate whether declarative memories in humans suffer spontaneous labilization/stabilization processes after learning or if they only pass through a single time window of lability."Póster Emotional episodic memory formation during Covid-19 quarentine: preliminary results(2020) León, Candela S.; Bonilla, Matías; Urreta Benítez, Facundo A.; Forcato, Cecilia"Episodic memory is the ability to recover past experiences and projects ourselves into the future. It is related to contextual information (both spatially and temporally). This type of memory is highly sensitive to aging, the passage of time, forgetfulness, interference and confusion. Furthermore, episodic memory processes are modulated by both anxiety and depression. People's mental health has deteriorated due to the Covid-19 pandemic, showing higher levels in both values. There is a general consensus that pleasant or aversive events are better remembered than neutral events. Regarding false memories, there is no such consensus. Some authors found that emotional content generates more false memories, however, it was also found that negative content reduces false memories. In this study we evaluated the effects of emotional variables, such as anxiety and depression, on memory encoding and consolidation of true and false details of aversive and neutral stories."Póster False memory formation during Covid-19 quarantine: age, sleep quality and emotional variables. Preliminary results(2020) Bonilla, Matías; León, Candela S.; Urreta Benítez, Facundo A.; Lippmann-Mazzaglia, Natalia; Calvo, Camila; Garrido, Manuel; Forcato, Cecilia"False memories are memories of events that did not happen or are altered in their content. It has been shown that not only small distortions can be introduced into old memories but also entire memories of events that never occurred can be implanted. Age is a crucial factor in the formation of false memories. Currently there is no consensus on which age range is more vulnerable. Since the COVID-19 pandemic, anxiety and depression values are increased and these factors also influence the formation of false memories.Thus, our aim was to study how age and mood factors, such as anxiety and depression, influence the formation of false memories."Póster Formación de memorias episódicas aversivas durante la pandemia por COVID-19(2021) León, Candela S.; Bonilla, Matías; Urreta Benítez, Facundo A.; Brusco, Luis Ignacio; Wang, Jingyi; Forcato, Cecilia"La memoria episódica es la capacidad de recordar qué, dónde y cuándo ocurrió un evento. Además, existe consenso en cuanto a que los eventos agradables o aversivos se recuerdan mejor que los eventos neutrales y que los procesos de memoria episódica están modulados por la ansiedad y la depresión. La salud mental de las personas se ha deteriorado debido a la pandemia de COVID-19, mostrando un aumento de los síntomas de ansiedad y depresión. Aquí, planteamos la hipótesis de que el aumento de síntomas negativos modifica la capacidad de codificar y consolidar recuerdos. Para estudiar esto, evaluamos los efectos del contexto emocional en la codificación y consolidación de recuerdos episódicos neutrales y aversivos."Póster The impact of sleep hygiene on emotional variables and memory processes in prision inmates(2021) Martín, Alejandra; Bonilla, Matías; Tassone, Leonela M.; Gallo, Francisco; Forcato, Cecilia"Having a good sleep quality is essential for a healthy life. Lack or poor quality of sleep can negatively affect various brain functions such as emotional processing and memory acquisition and consolidation. In addition, prolonged sleep deprivation, as well as the deterioration of the sleep quality are correlated with depressed mood, anger, aggressive behavior and anxiety. The prison experience can be inherently stressful and lead to disturbed sleep patterns. In prison, the most common sleep disorder is insomnia. When left untreated, it can negatively affect daytime functioning and work productivity, and it can influence inmate adverse behavior such as exacerbating irritability or aggression. Improving sleep in prison offers the potential to positively impact several of these common risk factors for both staff and inmates. Thus, we propose a sleep hygiene treatment to improve sleep habits in the prison environment. Here, we will discuss the project and preliminary data of one-month treatment of sleep hygiene in prison inmates."Póster The impact of time, age and frequency of use on recognizing personal items of our closest ones: Forensic implications. Preliminary results(2021) Bonilla, Matías; Vidal, Vanesa; León, Candela S.; Urreta Benítez, Facundo A.; Forcato, Cecilia"Sometimes people have to recognize belongings of close ones that were found in places where, for example, genocides took place. This is done in order to pinpoint a missing person's last whereabouts and in some cases because the family asks to keep with their belongings. To do this, one part of the process is asking the relatives of the missing person to identify the items. However, in some cases (e.g. the missing people during the last Argentine military dictatorship) these procedures have been put in doubt by the legal system in order to prevent errors such as two or more families recognizing the same item as their own and thus to prevent nonsense re-exposure to traumatic memories. To the best of our knowledge, there is a lack of studies evaluating our performance on recognition of clothes from close ones. It is known that our capacity to correctly recognize items depends on various factors, such as age, frequency of item exposure, level of stress, sleep, among others [1-4]. Here, we will discuss preliminary data of how different factors such as time, age and frequency of use modulate the capacity to correctly and falsely recognize personal items of close ones. These results can enlighten and help the everyday practice of organizations such asthe “Argentine Team of Forensic Anthropology” (EAAF) to make decisions about the reliability of the clothing recognition by the victim’s relatives."Póster Impairment of aversive episodic memories during covid-19 pandemic: The impact of emotional context on memory processes(2021) León, Candela S.; Bonilla, Matías; Urreta Benítez, Facundo A.; Brusco, Luis Ignacio; Wang, Jingyi; Forcato, Cecilia"Episodic memory is the ability to recall about what, where and when the event happened. Furthermore, there is a consensus that pleasant or aversive events are better remembered than neutral events and that episodic memory processes are modulated by anxiety and depression. People's mental health has deteriorated due to the COVID-19 pandemic, showing a growth in anxiety and depressive symptoms. Here, we hypothesize that the increase in negative symptoms modifies the ability to encode and consolidate memories. To study this, we evaluated the effects of emotional context on encoding and consolidation of aversive and neutral episodic memories."Póster Non-linear susceptibility to interferences in declarative memory formation(2021) Moyano, Malen D.; Carbonari, Giulia; Bonilla, Matías; Brusco, Luis Ignacio; Pedreira, María Eugenia; Kaczer, Laura; Forcato, Cecilia"After encoding, memories are in a labile state followed by a stabilization process known as consolidation. Once consolidated they can enter a new labile state after the presentation of a reminder (cue) of the original memory, followed by a period of re-stabilization (reconsolidation). In both processes, once stabilization/re-stabilization is accomplished the memory cannot be modified. Currently there are studies that show a rapid stabilization after 30 min, while others studies show that stabilization occurs after 6h. However, there are no studies evaluating short and long delays simultaneously. Knowing that there are spontaneous waves of destabilization (without the re-exposure to keys linked to learning) on which the consolidation and memory persistence depends, here we investigate whether declarative memories in humans go through spontaneous abilization/stabilization processes after learning or if they only pass through a single time window of lability."Póster Performance in lineups during covid-19 pandemic: influence of lock-down side effects(2021) Urreta Benítez, Facundo A.; León, Candela S.; Bonilla, Matías; Flores-Kanter, Pablo Ezequiel; Forcato, Cecilia"Our main objective was to study the impact of emotional and behavioral variables in the witnessing processes, using a natural context that generates conditions like those of a real crime."Póster Synaptic homeostasis and fake news(2021) León, Candela S.; Bonilla, Matías; Forcato, Cecilia; Urreta Benítez, Facundo A."The spread of fake news has become a major problem for societies. Recent studies showed that when people are confronted with invented news, can believe and even generate a false memory of these events, and this is increased when the content of the fake material is consistent with their ideology. Further, it has been observed that there are individual factors such as cognitive or analytical thinking abilities that influence the generation of false memories. Besides, a recent study found that decision-making is a result of the combination of the person's chronotype and the sleep pressure they have at the time of the evaluation. Here, we hypothesize that people's sleep pressure when observing fake news is a predictor of the capacity to generate false memories about fake news. To study this, we developed a set of fake news that was presented mixed with real news. We discuss the results in the framework of the Synaptic Homeostasis Hypothesis."