Non-linear susceptibility to interferences in declarative memory formation

Moyano, Malen D.; Carbonari, Giulia; Bonilla, Matías; Pedreira, María Eugenia; Brusco, Luis Ignacio; Kaczer, Laura; Forcato, Cecilia

Artículo de Publicación Periódica:
Non-linear susceptibility to interferences in declarative memory formation

dc.contributor.author	Moyano, Malen D.
dc.contributor.author	Carbonari, Giulia
dc.contributor.author	Bonilla, Matías
dc.contributor.author	Pedreira, María Eugenia
dc.contributor.author	Brusco, Luis Ignacio
dc.contributor.author	Kaczer, Laura
dc.contributor.author	Forcato, Cecilia
dc.date.accessioned	2022-10-31T19:02:05Z
dc.date.available	2022-10-31T19:02:05Z
dc.date.issued	2022-06-29
dc.description.abstract	"After encoding, memories go through a labile state followed by a stabilization process known as consolidation. Once consolidated they can enter a new labile state after the presentation of a reminder of the original memory, followed by a period of re-stabilization (reconsolidation). During these periods of lability the memory traces can be modified. Currently, some studies show a rapid stabilization after 30 min, while others show that stabilization occurs after longer periods (e.g. > 6 h). Here we investigate the effect of an interference treatment on declarative memory consolidation, comparing distinct time intervals after acquisition. On day 1, participants learned a list of non- syllable pairs (List 1). 5 min, 30 min, 3 h or 8 h later, they received an interference list (List 2) that acted as an amnesic agent. On day 2 (48 h after training) participants had to recall List 1 first, followed by List 2. We found that the List 1 memory was susceptible to interference when List 2 was administered 5 min or 3 h after learning but not when it was administered 30 min or 8 h after. We propose the possibility that this rapid memory protection could be induced by a fast and transient neocortical integration. Our results open a discussion about the contribution of molecular and systemic aspects to memory consolidation."
dc.identifier.uri	https://ri.itba.edu.ar/handle/123456789/3947
dc.language.iso	en
dc.relation	info:eu-repo/semantics/dataset/doi/10.1371/journal.pone.0270678
dc.relation	info:eu-repo/grantAgreement/CONICET/PICT/2016-0229/AR. Ciudad Autónoma de Buenos Aires
dc.rights	https://creativecommons.org/licenses/by-nc-sa/X.0/
dc.subject	CONSOLIDACION DE LA MEMORIA	es
dc.subject	MEMORIA	es
dc.subject	CEREBRO	es
dc.title	Non-linear susceptibility to interferences in declarative memory formation
dc.type	Article
dc.type	info:eu-repo/semantics/publishedVersion
dspace.entity.type	Artículo de Publicación Periódica
itba.description.filiation	Fil: Moyano, Malen D. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina.
itba.description.filiation	Fil: Carbonari, Giulia. Instituto Tecnológico de Buenos Aires; Argentina.
itba.description.filiation	Fil: Bonilla, Matías. Instituto Tecnológico de Buenos Aires; Argentina.
itba.description.filiation	Fil: Bonilla, Matías. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina.
itba.description.filiation	Fil: Pedreira, María Eugenia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina.
itba.description.filiation	Fil: Pedreira, María Eugenia. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina.
itba.description.filiation	Fil: Brusco, Luis Ignacio. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina.
itba.description.filiation	Fil: Brusco, Luis Ignacio. Universidad de Buenos Aires. Facultad de Ciencias Médicas; Argentina.
itba.description.filiation	Fil: Forcato, Cecilia. Instituto Tecnológico de Buenos Aires; Argentina.
itba.description.filiation	Fil: Forcato, Cecilia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina.
itba.description.filiation	Fil: Moyano, Malen D. Instituto Tecnológico de Buenos Aires; Argentina.